Patient preferences for disease-modifying drugs in multiple sclerosis therapy: a choice-based conjoint analysis

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Patient preferences for disease-modifying drugs in multiple sclerosis therapy: a choice-based conjoint analysis.

OBJECTIVES With an increasing number of disease-modifying treatments (DMTs) for multiple sclerosis (MS), patient preferences will gain importance in the decision-making process. We assessed patients' implicit preferences for oral versus parenteral DMTs and identified factors influencing patients' treatment preference. METHODS Patients with relapsing-remitting MS (n = 156) completed a question...

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Patient preferences for treatment of multiple sclerosis with disease-modifying therapies: a discrete choice experiment

OBJECTIVES To assess disease-modifying therapy (DMT) preferences in a population of patients with multiple sclerosis (MS) and to estimate the association between sociodemographic and clinical factors and these preferences. METHODS Preferences for DMTs attributes were measured using a discrete choice experiment. Analysis of preferences was assessed using mixed-logit hierarchical Bayes regressi...

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Disease Modifying Therapy in Multiple Sclerosis

Multiple sclerosis is an autoimmune disease of the central nervous system characterized by inflammatory demyelination and axonal degeneration. It is the commonest cause of permanent disability in young adults. Environmental and genetic factors have been suggested in its etiology. Currently available disease modifying drugs are only effective in controlling inflammation but not prevention of neu...

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cost-utility analysis of disease-modifying drugs in relapsing-remitting multiple sclerosis in iran.

background: disease-modifying drugs (dmds) are a significant expenditure for treating multiple sclerosis (ms). however, there is limited report on assessment of the cost-utility of dmds compared with symptom management in the presence of long-term data. this study aimed to assess the lifetime cost-utility from the iranian healthcare perspectives of 4dmds relative to symptom management alone in ...

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Conjoint analysis to understand preferences of patients with multiple sclerosis for disease-modifying therapy attributes in Spain: a cross-sectional observational study

OBJECTIVE To assess patients' preferences for a range of disease-modifying therapy (DMT) attributes in multiple sclerosis (MS). DESIGN A cross-sectional observational study. SETTING The data reported were from 17 MS units throughout Spain. PARTICIPANTS Adult patients with relapsing-remitting MS. MAIN OUTCOME A conjoint analysis was applied to assess preferences. A total of 221 patients ...

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ژورنال

عنوان ژورنال: Therapeutic Advances in Neurological Disorders

سال: 2014

ISSN: 1756-2864,1756-2864

DOI: 10.1177/1756285614555335